Enzymatic production of D-(-)-pantoyl lactone from ketopantoyl lactone.
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چکیده
منابع مشابه
Ketopantoyl lactone and ketopantoic acid reductases. Characterization of the reactions and purification of two forms of ketopantoyl lactone reductase.
Spectral and chromatographic data as well as methods for synthesis of 14C-labeled ketopantoic acid, ketopantoyl lactone, pantoic acid, and pantoyl lactone are presented. The products of ketopantoic acid and ketopantoyl lactone reductases were characterized as pantoic acid and pantoyl lactone, respectively. Unlike pantoyl lactone, ketopantoyl lactone spontaneously hydrolyzes and has a half-life ...
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The stereospecificity of hydrogen transfer from NADPH to the appropriate carbonyl substrate catalyzed by ketopantoic acid and ketopantoyl acid and ketopantoyl lactone reductases of yeast (Saccharomyces cerevisiae) and Escherichia coli has been determined. Yeast and E. coli ketopantoic acid reductases are B-specific enzymes which transfer hydrogen from [4B-3H]-NADPH to ketopantoic acid to form [...
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The actinomycins constitute a family of chromopeptide antibiotics containing an aminophenoxazinone chromophore attached to two pentapeptide lactone units of variable amino acid content1}. It was postulated as early as 1956 that the final step in the biosynthesis of an actinomycin involves the oxidative condensation of two molecules of a 3-hydroxy-4-methylanthraniloyl (4-MHA) peptide lactone2) (...
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In this study, the ability of two antibiotics daptomycin and pantoyl lactone to inhibit growth of horse originated pathogen Streptococcus equi by disrupting plasma membrane of the bacterium was investigated using agar diffusion and micro tube dilution methods. The results obtained from this study indicated that daptomycin was more effective in inhibiting the growth of the pathogen in vitro than...
متن کامل5-O-Acetyl-d-ribono-1,4-lactone
The title compound, C(7)H(10)O(6), was obtained from a regioselective enzyme-catalysed acyl-ation of d-ribono-1,4-lactone. The five-membered ring of the acyl-ated sugar shows an envelope conformation. In the crystal, the mol-ecules are linked by inter-molecular O-H⋯O hydrogen-bonds, forming a one-dimensional polymeric structure parallel to [010]. In addition, packing analysis shows stacking alo...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1987
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.51.3011